Inhaltsverzeichnis
The authors conclude that while modafinil probably exerts its effects via more than one mechanism, modafinil’s occupancy of the DAT probably plays a role in its pharmacological effects that should be further investigated. Hou et al studied the autonomic effects of modafinil in humans. They found that modafinil affects the locus coeruleus, which mediates pupil diameter and arousal, but it does not affect other autonomic functions, which are controlled by noreadrenergic control centers (A1 – A5) located outside of the locus coeruleus. Lin et al examined fos immunoreactivity in 26 brain sites of cats after the administration of amphetamine, methylphenidate, or modafinil. They found that modafinil induced very little fos-like immunoreactivity in the cortex, but it did induce fos labeling in the anterior hypothalamus and nearby areas, in contrast to amphetamine and methylphenidate. They also noted no fos labeling in the basal forebrain, thalamus, posterior hypothalamus, or the midbrain tegmentum as a result of modafinil administration.
- Lorazepamlorazepam increases and modafinil decreases sedation.
- Talk to your doctor about types of birth control that will work for you during and after your treatment with modafinil.
- Dose adjustments of these drugs and other drugs that are substrates for CYP2C19 may be necessary when used concomitantly with PROVIGIL .
- Chloral hydratechloral hydrate increases and modafinil decreases sedation.
However, your child’s doctor may decide the benefits of taking this drug may outweigh the risks. Talk with the doctor if you have questions about giving this valacyclovir drug to your child. Mental or mood problems like depression and suicidal thoughts have happened with this drug. Sometimes, people needed to get treated in a hospital. If you have ever had any mental or mood problems, talk with your doctor. Avoid driving and doing other tasks or actions that call for you to be alert until you see how this drug affects you.
What Is This Drug Used For?
The drug interacts unpredictably with alcohol in many individuals to cause serious liver toxicity and the economic costs of APAP toxicity are estimated to be in the hundred of millions of dollars/yr. I note that few,if any other PRESCRIPTION, let alone OTC drug, with a decades long history of steadily escalating injury and death to the population. By contrast, Vioxx was a dream drug! So it is the hypocrisy and unfairness of the treatment of Vioxx that I find objectionable. As in my melatonin page, we’ll assume the value of our time is measured by the minimum wage. We’ll also assume modafinil costs $3 a day (this adds 50% to be conservative).
Sleep Quiz: Sleep Hygiene & Sleep Facts
Get medical help right away if you have signs like red, swollen, blistered, or peeling skin ; red or irritated eyes; or sores in your mouth, throat, nose, or eyes. Check blood pressure and heart rate as the doctor has told you. Tell all of your health care providers that you take this drug.
Read it again each time this drug is refilled. If you have any questions about this drug, please talk with the doctor, pharmacist, or other health care provider. Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider. Birth control pills and other hormone-based birth control may not work as well to prevent pregnancy.